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Physical Methods Of Gene Therapy With Non Viral Vectorstbl

This post categorized under Vector and posted on January 9th, 2019.
Non-Viral Vectors Gene Gun: Physical Methods Of Gene Therapy With Non Viral Vectorstbl

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Considering the number of research groups that focus their investigations on the development of new vectors for gene therapy together with the advances in the development of new technologies to better understand their in vitro and in vivo behavior the present limitations of non-viral vectors will be resolved rationally.Non-viral methods present certain advantages over viral methods with simple large scale production and low host immunogenicity being just two. Previously low levels of transfection and expression of the gene held non-viral methods at a disadvantage however recent advances in vector technology have yielded molecules and techniques with transfection efficiencies similar to those of viruses .Evaluation of the Immune Response After Administration of Plasmid DNA-Non-viral Vector Complexes Fuminori Sakurai Yoshivectoru Takakura Mitsuru Hashida Pages 339-347


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